ITT4504
ITT4504
- Catalog: ITT4504
- Gene/Protein: TAS2R10
- Product Description: Immunotag™ T2R10 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | T2R10 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human TAS2R10. AA range:122-171 |
Specificity | T2R10 Polyclonal Antibody detects endogenous levels of T2R10 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TAS2R10 |
Accession No. | Q9NYW0 |
Alternate Names | TAS2R10; Taste receptor type 2 member 10; T2R10; Taste receptor family B member 2; TRB2 |
Description | taste 2 receptor member 10(TAS2R10) Homo sapiens This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Taste transduction, |
Protein Expression | Brain, |
Subcellular Localization | plasma membrane,integral component of membrane, |
Protein Function | function:Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |