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ITT4504

ITT4504
ITT4504
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$424.00
Price in reward points: 424
  • Catalog: ITT4504
  • Gene/Protein: TAS2R10
  • Product Description: Immunotag™ T2R10 Polyclonal Antibody

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Immunotag™ T2R10 Polyclonal Antibody
Antibody Specification
Datasheet
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein T2R10
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TAS2R10. AA range:122-171
Specificity T2R10 Polyclonal Antibody detects endogenous levels of T2R10 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TAS2R10
Accession No. Q9NYW0
Alternate Names TAS2R10; Taste receptor type 2 member 10; T2R10; Taste receptor family B member 2; TRB2
Description taste 2 receptor member 10(TAS2R10) Homo sapiens This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Taste transduction,
Protein Expression Brain,
Subcellular Localization plasma membrane,integral component of membrane,
Protein Function function:Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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