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ITT4705

ITT4705
ITT4705
ITT4705
  • Catalog: ITT4705
  • Gene/Protein: TP53INP1
  • Product Description: Immunotag™ TP53INP1 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ TP53INP1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein TP53INP1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TP53INP1. AA range:171-220
Specificity TP53INP1 Polyclonal Antibody detects endogenous levels of TP53INP1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TP53INP1
Accession No. Q96A56 Q9QXE4
Alternate Names TP53INP1; P53DINP1; SIP; Tumor protein p53-inducible nuclear protein 1; Stress-induced protein; p53-dependent damage-inducible nuclear protein 1; p53DINP1
Description function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,
Protein Expression Lung,Thymus,
Subcellular Localization nucleus,nucleoplasm,cytoplasm,autophagosome,cytosol,PML body,cytoplasmic vesicle,
Protein Function function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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