ITT4705
ITT4705
- Catalog: ITT4705
- Gene/Protein: TP53INP1
- Product Description: Immunotag™ TP53INP1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TP53INP1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human TP53INP1. AA range:171-220 |
Specificity | TP53INP1 Polyclonal Antibody detects endogenous levels of TP53INP1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TP53INP1 |
Accession No. | Q96A56 Q9QXE4 |
Alternate Names | TP53INP1; P53DINP1; SIP; Tumor protein p53-inducible nuclear protein 1; Stress-induced protein; p53-dependent damage-inducible nuclear protein 1; p53DINP1 |
Description | function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed., |
Protein Expression | Lung,Thymus, |
Subcellular Localization | nucleus,nucleoplasm,cytoplasm,autophagosome,cytosol,PML body,cytoplasmic vesicle, |
Protein Function | function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |