ITT4964
ITT4964
- Catalog: ITT4964
- Gene/Protein: ZNF397
- Product Description: Immunotag™ ZNF397 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ZNF397 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZNF397. AA range:10-59 |
| Specificity | ZNF397 Polyclonal Antibody detects endogenous levels of ZNF397 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ZNF397 |
| Accession No. | Q8NF99 |
| Alternate Names | ZNF397; ZNF47; ZSCAN15; Zinc finger protein 397; Zinc finger and SCAN domain-containing protein 15; Zinc finger protein 47 |
| Description | zinc finger protein 397(ZNF397) Homo sapiens This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq, Oct 2009], |
| Protein Expression | Hepatoma,Mammary gland,Uterus, |
| Subcellular Localization | nucleus,cytoplasm, |
| Protein Function | function:Isoform 3 acts as a DNA-dependent transcriptional repressor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 SCAN box domain.,similarity:Contains 9 C2H2-type zinc fingers.,subunit:Isoforms 1 and 3 can both homo- and hetero-associate. Homo-association of isoform 1 is dependent on the presence of the SCAN domain.,tissue specificity:Expressed strongly in testis, moderately in skeletal muscle, pancreas and prostate, and weakly in heart, placenta, liver, kidney, spleen, thymus and small intestine., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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