ITT5079
ITT5079
ITT5079
from
$424.00
Price in reward points: 424
- Catalog: ITT5079
- Gene/Protein: MPHOSPH10
- Product Description: Immunotag™ MPP10 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MPP10 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen Synthesized peptide derived from MPP10 . at AA range: 60-140 Specificity MPP10 Polyclonal Antibody detects endogenous levels of MPP10 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name MPHOSPH10 Accession No. O00566 Q810V0 Alternate Names MPHOSPH10; MPP10; U3 small nucleolar ribonucleoprotein protein MPP10; M phase phosphoprotein 10 Description M-phase phosphoprotein 10(MPHOSPH10) Homo sapiens This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010], Protein Expression Blood,Brain,Epithelium,Mammary cancer,Placenta,Prostate, Subcellular Localization nucleoplasm,chromosome,nucleolus,small nucleolar ribonucleoprotein complex,small-subunit processome,Mpp10 complex, Protein Function function:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.,PTM:Phosphorylated in M (mitotic) phase.,similarity:Belongs to the MPP10 family.,subcellular location:Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin.,subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with IMP3 and IMP4., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MPP10 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from MPP10 . at AA range: 60-140 |
| Specificity | MPP10 Polyclonal Antibody detects endogenous levels of MPP10 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MPHOSPH10 |
| Accession No. | O00566 Q810V0 |
| Alternate Names | MPHOSPH10; MPP10; U3 small nucleolar ribonucleoprotein protein MPP10; M phase phosphoprotein 10 |
| Description | M-phase phosphoprotein 10(MPHOSPH10) Homo sapiens This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010], |
| Protein Expression | Blood,Brain,Epithelium,Mammary cancer,Placenta,Prostate, |
| Subcellular Localization | nucleoplasm,chromosome,nucleolus,small nucleolar ribonucleoprotein complex,small-subunit processome,Mpp10 complex, |
| Protein Function | function:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.,PTM:Phosphorylated in M (mitotic) phase.,similarity:Belongs to the MPP10 family.,subcellular location:Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin.,subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with IMP3 and IMP4., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |