ITT5131
ITT5131
ITT5131
from
$424.00
Price in reward points: 424
- Catalog: ITT5131
- Gene/Protein: TXNDC17
- Product Description: Immunotag™ TRP14 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein TRP14 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen Synthesized peptide derived from TRP14 . at AA range: 20-100 Specificity TRP14 Polyclonal Antibody detects endogenous levels of TRP14 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name TXNDC17 Accession No. Q9BRA2 Q9CQM5 Alternate Names TXNDC17; TXNL5; Thioredoxin domain-containing protein 17; 14 kDa thioredoxin-related protein; TRP14; Protein 42-9-9; Thioredoxin-like protein 5 Description function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines., Protein Expression Skin,Umbilical vein endothelial cell, Subcellular Localization cytosol,extracellular exosome, Protein Function function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | TRP14 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from TRP14 . at AA range: 20-100 |
| Specificity | TRP14 Polyclonal Antibody detects endogenous levels of TRP14 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TXNDC17 |
| Accession No. | Q9BRA2 Q9CQM5 |
| Alternate Names | TXNDC17; TXNL5; Thioredoxin domain-containing protein 17; 14 kDa thioredoxin-related protein; TRP14; Protein 42-9-9; Thioredoxin-like protein 5 |
| Description | function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines., |
| Protein Expression | Skin,Umbilical vein endothelial cell, |
| Subcellular Localization | cytosol,extracellular exosome, |
| Protein Function | function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |