ITT5139
ITT5139
ITT5139
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$424.00
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- Catalog: ITT5139
- Gene/Protein: HSPBAP1
- Product Description: Immunotag™ HSPBAP1 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein HSPBAP1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen The antiserum was produced against synthesized peptide derived from the Internal region of human HSPBAP1. AA range:321-370 Specificity HSPBAP1 Polyclonal Antibody detects endogenous levels of HSPBAP1 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name HSPBAP1 Accession No. Q96EW2 Q8BK58 Alternate Names HSPBAP1; PASS1; HSPB1-associated protein 1; 27 kDa heat shock protein-associated protein 1; Protein associated with small stress protein 1 Description HSPB1 associated protein 1(HSPBAP1) Homo sapiens This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011], Protein Expression Fetal brain,Human small intestine,Lung,Ovary,Placenta,Prostate, Subcellular Localization cytoplasm, Protein Function disease:A chromosomal aberration involving HSPBAP1 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.,function:May play a role in cellular stress response.,similarity:Contains 1 JmjC domain.,subunit:Interacts with CRYAB and HSPB1.,tissue specificity:Widely expressed., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | HSPBAP1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human HSPBAP1. AA range:321-370 |
| Specificity | HSPBAP1 Polyclonal Antibody detects endogenous levels of HSPBAP1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | HSPBAP1 |
| Accession No. | Q96EW2 Q8BK58 |
| Alternate Names | HSPBAP1; PASS1; HSPB1-associated protein 1; 27 kDa heat shock protein-associated protein 1; Protein associated with small stress protein 1 |
| Description | HSPB1 associated protein 1(HSPBAP1) Homo sapiens This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011], |
| Protein Expression | Fetal brain,Human small intestine,Lung,Ovary,Placenta,Prostate, |
| Subcellular Localization | cytoplasm, |
| Protein Function | disease:A chromosomal aberration involving HSPBAP1 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.,function:May play a role in cellular stress response.,similarity:Contains 1 JmjC domain.,subunit:Interacts with CRYAB and HSPB1.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |