ITT5144
ITT5144
- Catalog: ITT5144
- Gene/Protein: PPID
- Product Description: Immunotag™ Cyclophilin D Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CyclophIL-in D |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Cyclophilin D, at AA range: 321-370 |
| Specificity | Cyclophilin D Polyclonal Antibody detects endogenous levels of Cyclophilin D protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PPID |
| Accession No. | Q08752 Q9CR16 Q6DGG0 |
| Alternate Names | PPID; CYP40; CYPD; Peptidyl-prolyl cis-trans isomerase D; PPIase D; 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin-40; CYP-40; Cyclophilin-related protein; Rotamase D |
| Description | peptidylprolyl isomerase D(PPID) Homo sapiens The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Calcium,Parkinson's disease,Huntington's disease, |
| Protein Expression | Brain,Pancreas,Placenta,Platelet,Uterus, |
| Subcellular Localization | nucleus,nucleoplasm,nucleolus,cytoplasm, |
| Protein Function | catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Less sensitive to inhibition by cyclosporin A than is CYP-18.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,online information:Cyclophilin entry,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.,similarity:Contains 1 PPIase cyclophilin-type domain.,similarity:Contains 3 TPR repeats.,subunit:Binds ESR1.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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