ITT5169
ITT5169
- Catalog: ITT5169
- Gene/Protein: FGF6
- Product Description: Immunotag™ FGF-6 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | FGF-6 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF6. AA range:159-208 |
Specificity | FGF-6 Polyclonal Antibody detects endogenous levels of FGF-6 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FGF6 |
Accession No. | P10767 P21658 |
Alternate Names | FGF6; HST2; HSTF2; Fibroblast growth factor 6; FGF-6; Heparin secretory-transforming protein 2; HST-2; HSTF-2; Heparin-binding growth factor 6; HBGF-6 |
Description | fibroblast growth factor 6(FGF6) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Regulates Actin and Cytoskeleton,Pathways in cancer,Melanoma, |
Subcellular Localization | extracellular region,extracellular space,intracellular,sarcolemma, |
Protein Function | function:Can transform NIH 3T3 cells. Exhibits strong mitogenic and angiogenic properties.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Leukemia cell lines with platelet/ megakaryocytic differentiation potential., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |