ITT5517
ITT5517
ITT5517
from
$424.00
Price in reward points: 424
- Catalog: ITT5517
- Gene/Protein: MAG
- Product Description: Immunotag™ MAG Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MAG Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from MAG, at AA range: 501-550 Specificity MAG Polyclonal Antibody detects endogenous levels of MAG protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name MAG Accession No. P20916 P20917 P07722 Alternate Names MAG; GMA; Myelin-associated glycoprotein; Siglec-4a Description myelin associated glycoprotein(MAG) Homo sapiens The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010], Cell Pathway/ Category Cell adhesion molecules (CAMs), Protein Expression Brain,Cerebellum,White Matter pool- 5 brain tissues- femoral artery, Subcellular Localization cytoplasm,plasma membrane,integral component of membrane,paranode region of axon,myelin sheath adaxonal region,Schmidt-Lanterman incisure,mesaxon, Protein Function function:Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid.,online information:Siglec-4,similarity:Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds to RTN4R., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MAG |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from MAG, at AA range: 501-550 |
| Specificity | MAG Polyclonal Antibody detects endogenous levels of MAG protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MAG |
| Accession No. | P20916 P20917 P07722 |
| Alternate Names | MAG; GMA; Myelin-associated glycoprotein; Siglec-4a |
| Description | myelin associated glycoprotein(MAG) Homo sapiens The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs), |
| Protein Expression | Brain,Cerebellum,White Matter pool- 5 brain tissues- femoral artery, |
| Subcellular Localization | cytoplasm,plasma membrane,integral component of membrane,paranode region of axon,myelin sheath adaxonal region,Schmidt-Lanterman incisure,mesaxon, |
| Protein Function | function:Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid.,online information:Siglec-4,similarity:Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds to RTN4R., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |