ITT5517
ITT5517
- Catalog: ITT5517
- Gene/Protein: MAG
- Product Description: Immunotag™ MAG Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | MAG |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from MAG, at AA range: 501-550 |
Specificity | MAG Polyclonal Antibody detects endogenous levels of MAG protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MAG |
Accession No. | P20916 P20917 P07722 |
Alternate Names | MAG; GMA; Myelin-associated glycoprotein; Siglec-4a |
Description | myelin associated glycoprotein(MAG) Homo sapiens The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010], |
Cell Pathway/ Category | Cell adhesion molecules (CAMs), |
Protein Expression | Brain,Cerebellum,White Matter pool- 5 brain tissues- femoral artery, |
Subcellular Localization | cytoplasm,plasma membrane,integral component of membrane,paranode region of axon,myelin sheath adaxonal region,Schmidt-Lanterman incisure,mesaxon, |
Protein Function | function:Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid.,online information:Siglec-4,similarity:Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds to RTN4R., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |