ITT5700
ITT5700
- Catalog: ITT5700
- Gene/Protein: C7
- Product Description: Immunotag™ C7 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | C7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human C7. AA range:100-150 |
| Specificity | C7 Polyclonal Antibody detects endogenous levels of C7 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | C7 |
| Accession No. | P10643 |
| Alternate Names | C7; Complement component C7 |
| Description | complement C7(C7) Homo sapiens C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Complement and coagulation cascades,Prion diseases,Systemic lupus erythematosus, |
| Protein Expression | Liver,Placenta,Plasma,PNS, |
| Subcellular Localization | extracellular region,membrane attack complex,extracellular exosome, |
| Protein Function | disease:Defects in C7 are a cause of component C7 deficiency (C7D) [MIM:217070]. Patients with C7D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.,function:C7 is a constituent of the membrane attack complex. C7 binds to C5b forming the C5b-7 complex, where it serves as a membrane anchor.,online information:C7 mutation db,PTM:C7 has 28 disulfide bridges.,similarity:Belongs to the complement C6/C7/C8/C9 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MACPF domain.,similarity:Contains 2 Sushi (CCP/SCR) domains.,similarity:Contains 2 TSP type-1 domains.,subunit:Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|