ITT5759
ITT5759
ITT5759
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- Catalog: ITT5759
- Gene/Protein: PIK3C3 VPS34
- Product Description: Immunotag™ PI 3 Kinase Class 3 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein PI 3 Kinase Class 3 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000, ELISA 1:10000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat,Predicted:Cow:PIG Host Species Rabbit Immunogen Synthetic Peptide of PI 3 Kinase Class 3 Specificity PI 3 Kinase Class 3 Polyclonal Antibody detects endogenous levels of PI 3 Kinase Class 3 Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name PIK3C3 VPS34 Accession No. Q8NEB9 Q6PF93 O88763 Alternate Names phosphoinositide-3-kinase, class 3 Description catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle., Cell Pathway/ Category Inositol phosphate metabolism,Phosphatidylinositol signaling system,Regulation of autophagy, Protein Expression Testis,Uterus, Subcellular Localization intracellular,late endosome,cytosol,axoneme,phosphatidylinositol 3-kinase complex,membrane,midbody,phagocytic vesicle membrane,phosphatidylinositol 3-kinase complex, class III,autolysosome, Protein Function catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | PI 3 Kinase Class 3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Predicted:Cow:PIG |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of PI 3 Kinase Class 3 |
| Specificity | PI 3 Kinase Class 3 Polyclonal Antibody detects endogenous levels of PI 3 Kinase Class 3 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PIK3C3 VPS34 |
| Accession No. | Q8NEB9 Q6PF93 O88763 |
| Alternate Names | phosphoinositide-3-kinase, class 3 |
| Description | catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle., |
| Cell Pathway/ Category | Inositol phosphate metabolism,Phosphatidylinositol signaling system,Regulation of autophagy, |
| Protein Expression | Testis,Uterus, |
| Subcellular Localization | intracellular,late endosome,cytosol,axoneme,phosphatidylinositol 3-kinase complex,membrane,midbody,phagocytic vesicle membrane,phosphatidylinositol 3-kinase complex, class III,autolysosome, |
| Protein Function | catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |