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ITT5894

ITT5894-4
ITT5894-2
ITT5894-3
ITT5894
ITT5894-5
ITT5894-4
ITT5894-2
ITT5894-3
ITT5894
ITT5894-5
  • Gene/Protein: GREM2 CKTSF1B2 DAND3 PRDC
  • Product Description: Immunotag™ Gremlin-2 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

    Available Options

ITT5894

Immunotag™ Gremlin-2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Gremlin-2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from the Internal region of human GREM2. AA range:71-120
Specificity The antibody detects endogenous Gremlin-2
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name GREM2 CKTSF1B2 DAND3 PRDC
Accession No. Q9H772 O88273
Alternate Names Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)
Description gremlin 2, DAN family BMP antagonist(GREM2) Homo sapiens This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Colon,
Subcellular Localization extracellular region,extracellular space,
Protein Function function:Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Interacts with BMP2 and BMP4.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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