ITT6158
ITT6158
ITT6158
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$424.00
Price in reward points: 424
- Catalog: ITT6158
- Gene/Protein: GLP1R
- Product Description: Immunotag™ GLP1R Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein GLP1R Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000, ELISA 1:10000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from human GLP1R Polyclonal Specificity This antibody detects endogenous levels of GLP1R. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name GLP1R Accession No. P43220 O35659 P32301 Alternate Names Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R) Description glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], Cell Pathway/ Category Neuroactive ligand-receptor interaction, Protein Expression Gastric carcinoma,Insulinoma,Pancreas,Pancreatic islet,Placenta, Subcellular Localization intracellular,plasma membrane,integral component of membrane, Protein Function function:This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,online information:Glucagon-like peptide 1 entry,similarity:Belongs to the G-protein coupled receptor 2 family., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | GLP1R |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human GLP1R Polyclonal |
| Specificity | This antibody detects endogenous levels of GLP1R. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GLP1R |
| Accession No. | P43220 O35659 P32301 |
| Alternate Names | Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R) |
| Description | glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Gastric carcinoma,Insulinoma,Pancreas,Pancreatic islet,Placenta, |
| Subcellular Localization | intracellular,plasma membrane,integral component of membrane, |
| Protein Function | function:This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,online information:Glucagon-like peptide 1 entry,similarity:Belongs to the G-protein coupled receptor 2 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |