Clofazimine
Clofazimine
Clofazimine
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| RC-981 | Clofazimine | 5g | $300.00 |
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| RC-981 | Clofazimine | 5g | $300.00 |
Clofazimine is an active phenazine composed of an imino group and aromatic tricyclic heterocycles that is used as an antimycobacterial, anti-inflammatory and anti-cancer compound. It has been shown to be a potent in vivo antimycobacterial agent toward Mycobacterium leprae and in vitro to Mycobacterium avium.
As an anti-inflammatory, clofazimine inhibits reactive oxygen species (ROS) formation within neutrophils by inhibiting myeloperoxidase catalyzed reactions. The formed ROS are responsible for activating tumor necrosis factor alpha (TNFα) and interleukin 8 (IL8), which are inflammatory cytokines.
| CAS # | 2030-63-9 |
|---|---|
| MW | 473.40 g/mol |
| Storage | Store at room temperature. |
Clofazimine is an active phenazine composed of an imino group and aromatic tricyclic heterocycles that is used as an antimycobacterial, anti-inflammatory and anti-cancer compound. It has been shown to be a potent in vivo antimycobacterial agent toward Mycobacterium leprae and in vitro to Mycobacterium avium.
As an anti-inflammatory, clofazimine inhibits reactive oxygen species (ROS) formation within neutrophils by inhibiting myeloperoxidase catalyzed reactions. The formed ROS are responsible for activating tumor necrosis factor alpha (TNFα) and interleukin 8 (IL8), which are inflammatory cytokines.
| CAS # | 2030-63-9 |
|---|---|
| MW | 473.40 g/mol |
| Storage | Store at room temperature. |