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ASB-16 (2 Citations)

Structure of ASB-16

ASB-16 is a zwitterionic detergents composed of a sulfobetaine with a C16 alkyl tail that is highly efficient in solubilizing proteins for 2D electrophoresis analysis and other downstream applications.  Optimal solubility is achieved in Urea and thiourea buffers, but not in urea alone. 
  • Type: Zwitterionic detergent
  • Full Name: Amidosulfobetaine-16; 3-[N,N-Dimethyl-N-(3-palmitamidopropyl)ammonio]propane-1-sulfonate)
  • CAS #: 52562-29-5
  • Molecular Formula: C24H50N2O4S
  • Molecular Weight: 462.73
  • Form: White to off white powder
  • Purity: >99%
  • Solubility: Water soluble
  • Conductivity: <50µS in a 10% solution
  • Critical micelle concentration (CMC): 8mM (25°C)

Applications

  • Zwitterionic detergent.
  • Aminosulfobetaine with C16 alkyl tail.
  • In some cases superior than ASB-14.
  • Useful for solubilizing proteins for 2D analysis.
  • Optimal solubility achieved in urea-thiourea mixtures and not in urea alone.
  • Reported to show better protein solubilization properties than CHAPS.
  • ASB-16 has been shown to solubilize membrane proteins previously undetected.
Material Safety Data Sheet
DG062
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DG063
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish
Technical Literature
Detergent Handbook & Selection Guide A Comprehensive Guide to the Properties and Uses of Detergents in Research. Also features information on detergent removal systems.
Removing Detergents from Protein Solutions

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