ASB-16

• Type: Zwitterionic detergent
• Full Name: Amidosulfobetaine-16; 3-[N,N-Dimethyl-N-(3-palmitamidopropyl)ammonio]propane-1-sulfonate)
• CAS #: 52562-29-5
• Molecular Formula: C₂₄H₅₀N₂O₄S
• Molecular Weight: 462.73
• Form: White to off white powder
• Purity: >99%
• Solubility: Water soluble
• Conductivity: <50µS in a 10% solution
• Critical micelle concentration (CMC): 8mM (25°C)

Applications

• Zwitterionic detergent.
• Aminosulfobetaine with C₁₆ alkyl tail.
• In some cases superior than ASB-14.
• Useful for solubilizing proteins for 2D analysis.
• Optimal solubility achieved in urea-thiourea mixtures and not in urea alone.
• Reported to show better protein solubilization properties than CHAPS.
• ASB-16 has been shown to solubilize membrane proteins previously undetected.