CHAPS

CHAPS
Type: Zwitterionic detergent
 
Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
 
Mol. Formula: C32H58N2O7S
 
Mol Weight: 614.9
 


Form: White solid
 


Purity: >99%
 

Solubility: Water soluble
 


Conductivity: <25µS in a 10% solution
 


Critical micelle concentration (CMC): 6-10mM (25°C)
 


Aggregation number: 10
 


Cloud point: >100°C
 

Average micellar weight: 6150
 

Features

  • Zwitterionic detergent
  • Non-denaturing
  • Electrically neutral

 


Applications

  • Has all the advantages of sulfobetaine containing detergents: hydrophobic, bile salt, and anionic detergents in a single molecule.
  • Better at solubilizing proteins and breaking protein-protein interactions.
  • Less protein aggregation than non-ionic detergents.
  • Capable of solubilizing opiate receptors.
  • CHAPS can be removed from protein solutions with a detergent removing gel or by dialysis.

 

 

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Material Safety Data Sheet
DG049
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Technical Literature
Assay Development A handbook for selection of products for assay development, including coated plates, blocking agents, antibodies, enzymes and antibody labeling tools.
Detergent Handbook & Selection Guide A Comprehensive Guide to the Properties and Uses of Detergents in Research. Also features information on detergent removal systems.
Removing Detergents from Protein Solutions
Catalog Description Size Price(USD) Qty
DG049
CHAPS (3-(3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate) 1g
$21.00
DG050
CHAPS (3-(3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate) 5g
$52.00
DG051
CHAPS (3-(3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate) 25g
$198.00
DG096
CHAPS (3-(3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate) 100g
$769.00
DG097
CHAPS, 5% filtered solution 50ml
$102.00
DG098
CHAPS, 5% filtered solution 100ml
$200.00
DG099
CHAPS, 5% filtered solution 500ml
$969.00