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Type: Zwitterionic detergent
Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
Molecular Formula: C32H58N2O8S
Molecular Weight: 630.9
Form: White solid
Solubility: Water soluble
Conductivity: <50µS in a 10% solution
Critical micelle concentration (CMC): 8mM (25°C)
Aggregation number: 11
Cloud point: 90°C
Average micellar weight: 7000
- Zwitterionic detergent.
- Electrically neutral.
- Higher solubility than CHAPS because of a more polar head group.
- Solubilizes membrane proteins in their native state.
- Solubilizes opiate receptor to a state exhibiting reversible binding of opiates.
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