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Immobilized Guanosine 5′-triphosphate

Immobilized Guanosine 5′-triphosphate
Immobilized Guanosine 5′-triphosphate
Immobilized Guanosine 5′-triphosphate
Catalog Description Size Price (USD) Qty
786-1896Immobilized Guanosine 5′-triphosphate2 ml equivalent, dry form$307.00

GTP is immobilized on agarose using the primary amine on the guanidine ring via a 6-carbon space arm. 

 

Affinity Resin Preparation

Attachment of affinity ligands to immobilized supports can be accomplished using a wide variety of coupling chemistries, different linkers, and various ligand orientations to attach the ligand to the support. The linkers, ligand orientation, and coupling chemistry used can have widely varying effects on the affinity ligand's ability to bind to the desired target molecule during purification. The binding of a particular target using conditions established with another, similar resin may not always correlate directly. As such, optimization of the purification conditions may be required by the end user to achieve the desired results.

We have seen from previous studies that the linker molecule and ligand orientation used can have a significant influence on the purification results. GBio can manufacture affinity resins using any combination of coupling chemistry and linker to provide custom solutions for your research. Please inquire about our custom synthesis options.

 

Immobilized Guanosine 5′-triphosphate is affinity resin used in purifying guanosine binding proteins.

 

Click here to request bulk or custom sizes.

Features:

  • GTP coupled to 6% cross-linked Agarose
  • Extent of labeling is 1- 5 µmol GTP per ml resin 
  • ​Shipped as hydrated resin in 20% ethanol.
  • Available in 2 ml equivalent, dry form.   


Application(s):

  • Immobilized Guanosine 5′-triphosphate is affinity resin used in purifying guanosine binding proteins

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