Immobilized Pepstatin

G-Biosciences Immobilized Pepstatin is for the purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin. 

Pepstatin is isovaleryl-Val-Val-AHMHA-Ala-AHMHA where AHMHA= (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid and is a potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases.

The resin consists of 6% beaded agarose that is covalently coupled to pepstatin through a diaminodipropylamine spacer arm and has a binding capacity of 1-2mg pepsin per millimeter of settled resin.
 

Features

• Capacity: 1-2mg pepsin/ml resin
• 6% beaded agarose
• Diaminodipropylamine spacer arm

Applications

• Purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin