| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| RC-1116 | Thiostrepton | 1g | $184.00 | |
| RC-1117 | Thiostrepton | 5g | $629.00 |
Thiostrepton is a cyclic peptide antibiotic isolated from Streptomyces azureus. It targets a wide variety of gram-negative and gram-positive bacteria, especially those causing skin infections. It has been used as a marker for selection of recombinant Streptomyces cultures. Additionally, thiostrepton has been shown to inhibit FOXM1, a gene commonly overexpressed in cancer cell lines, thus inhibiting cancer cell growth. Thiostrepton functions by binding elongation factor G (EF-G) and interfering with ribosomal GTPase activity, ultimately inhibiting protein synthesis.
| CAS # | 1393-48-2 |
|---|---|
| MW | 1664.89 g/mol |
| Grade | MOLECULAR BIOLOGY GRADE |
| Storage | Store at -20°C. |
Thiostrepton is a cyclic peptide antibiotic isolated from Streptomyces azureus. It targets a wide variety of gram-negative and gram-positive bacteria, especially those causing skin infections. It has been used as a marker for selection of recombinant Streptomyces cultures. Additionally, thiostrepton has been shown to inhibit FOXM1, a gene commonly overexpressed in cancer cell lines, thus inhibiting cancer cell growth. Thiostrepton functions by binding elongation factor G (EF-G) and interfering with ribosomal GTPase activity, ultimately inhibiting protein synthesis.
| CAS # | 1393-48-2 |
|---|---|
| MW | 1664.89 g/mol |
| Grade | MOLECULAR BIOLOGY GRADE |
| Storage | Store at -20°C. |
