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Boronate Resin

Boronate Resin
Boronate Resin
Boronate Resin
Catalog Description Size Price (USD) Qty
786-314Boronate Resin (Dry Beads)5g$790.00
786-315Boronate Resin (Dry Beads)50g$7,008.00
786-823Boronate Resin (Suspension)2ml resin$146.00
786-313Boronate Resin (Suspension)10ml resin$320.00

Our Boronate resin is designed for the isolation of ribonucleotide and oligonucleotide RNA.

 

The resin consists of boronic acid covalently linked to a polyacrylamide support that offers simple isolation of small molecular weight compounds that have cis-diol groups.

 

Mechanism: The boronic acid interacts with the cis-diol groups, found in the sugar portion of nucleotides, forming a reversible five member ring complex. Impurities are washed away and then the complex dissociated by low pH or presence of sorbitol.

 

The polyacrylamide support excludes >6000 Da molecules from entering the resin bed and therefore is suitable only for small molecules.

 


Features

  • Polyacrylamide gel
  • >1.2meq/g boronate load capacity
  • >130µmol sorbitol/ml gel binding capacity
  • 6,000Da exclusion limit
  • 45-90µm wet bead size

 

 

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