ITA1651
ITA1651
- Catalog: ITA1651
- Gene/Protein: CDKN2A
- Product Description: Immunotag™ p16 INK Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | p16 INK |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500-1:2000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human p16 INK |
Specificity | p16 INK Antibody detects endogenous levels of total p16 INK |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | CDKN2A |
Accession No. | P42771 |
Alternate Names | CCM2; CDK4 inhibitor p16 INK4; CDK4I; CDKN2; CDKN2A; Cell cycle negative regulator beta; CMM2; Cyclin dependent kinase 4 inhibitor A; Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4); Cyclin Dependent Kinase Inhibitor 2A; Cyclin dependent kinase inhibitor 2A isoform 4; Cyclin dependent kinase inhibitor 2A isoforms 1/2/3; Cyclin dependent kinase inhibitor p16; INK4; INK4A; MLM; MTS1; Multiple tumor suppressor 1; p14; p16; P16INK4; p16INK4a; p19; p19Arf; TP16; |
Description | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 16 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |