ITA5140
ITA5140
- Catalog: ITA5140
- Gene/Protein: NOC2L
- Product Description: Immunotag™ NOC2L Antibody
385.0000
Price in reward points: 385
Your shopping cart is empty!
Antibody Specification | |
Datasheet | |
Target Protein | NOC2L |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | NOC2L Antibody detects endogenous levels of total NOC2L |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | NOC2L |
Accession No. | Q9Y3T9 |
Alternate Names | NET15; NET7; NIR; NOC2 like; NOC2 like nucleolar associated transcriptional repressor; NOC2-like protein; NOC2L; NOC2L nucleolar associated transcriptional repressor; NOC2L_HUMAN; Novel INHAT (inhibitor of histone acetyltransferase) repressor; Novel INHAT repressor; Nucleolar complex associated 2 homolog (S. cerevisiae); Nucleolar complex protein 2 homolog; PPP1R112; Protein NOC2 homolog; Protein phosphatase 1 regulatory subunit 12; |
Description | Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 85 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |