ITA5555
ITA5555
- Catalog: ITA5555
- Gene/Protein: TEAD3
- Product Description: Immunotag™ TEAD3 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TEAD3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | TEAD3 Antibody detects endogenous levels of total TEAD3 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | TEAD3 |
Accession No. | Q99594 |
Alternate Names | DTEF 1; DTEF-1; DTEF1; ETFR 1; ETFR1; TEA domain family member 3; TEA domain family member 5; TEAD 3; TEAD-3; Tead3; TEAD3_HUMAN; TEAD5; TEF 5; TEF5; Transcriptional enhancer factor 5; Transcriptional enhancer factor TEF 5 (DTEF 1); Transcriptional enhancer factor TEF 5; Transcriptional enhancer factor TEF-5; |
Description | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 49 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |