ITN0301
ITN0301
- Catalog: ITN0301
- Gene/Protein: CLC
- Product Description: Immunotag™ LPPL Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | LPPL |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
Specificity | LPPL Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | CLC |
Accession No. | Q05315 P97400 |
Description | Charcot-Leyden crystal galectin(CLC) Homo sapiens Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008], |
Subcellular Localization | cytosol, |
Protein Function | catalytic activity:2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate.,disease:Forms hexagonal bipyramidal crystals, known as Charcot-Leyden crystals, in tissues and secretions from sites of eosinophil-associated inflammation and some myeloid leukemias.,function:May have both lysophospholipase and carbohydrate-binding activities.,online information:Galectin-10,similarity:Contains 1 galectin domain.,subcellular location:Localized in granules from where it may be secreted or transported to other locations in the cell.,tissue specificity:Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |