ITN0875
ITN0875
- Catalog: ITN0875
- Gene/Protein: MNX1 HLXB9
- Product Description: Immunotag™ MNX1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MNX1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 260-340 |
Specificity | MNX1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | MNX1 HLXB9 |
Accession No. | P50219 Q9QZW9 |
Description | motor neuron and pancreas homeobox 1(MNX1) Homo sapiens This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009], |
Cell Pathway/ Category | Maturity onset diabetes of the young, |
Protein Expression | Placenta,Tonsil, |
Subcellular Localization | nucleus,nucleolus,cytoplasm, |
Protein Function | disease:Defects in MNX1 are a cause of Currarino syndrome [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.,function:Putative transcription factor involved in pancreas development and function.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in lymphoid and pancreatic tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |