ITN0921
ITN0921
- Catalog: ITN0921
- Gene/Protein: NDUFA5
- Product Description: Immunotag™ NDUA5 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NDUA5 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 10-90 |
Specificity | NDUA5 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NDUFA5 |
Accession No. | Q16718 Q9CPP6 Q63362 |
Description | NADH:ubiquinone oxidoreductase subunit A5(NDUFA5) Homo sapiens This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014], |
Cell Pathway/ Category | Oxidative phosphorylation,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
Protein Expression | Lung,Mammary gland,Placenta,Retina,Skeletal muscle, |
Subcellular Localization | mitochondrial inner membrane,mitochondrial respiratory chain complex I, |
Protein Function | function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA5 subunit family.,subunit:Complex I is composed of 45 different subunits.,tissue specificity:Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |