ITN2558
ITN2558
- Catalog: ITN2558
- Gene/Protein: LGR5 GPR49 GPR67
- Product Description: Immunotag™ LGR5 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | LGR5 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | LGR5 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | LGR5 GPR49 GPR67 |
Accession No. | O75473 Q9Z1P4 |
Description | leucine rich repeat containing G protein-coupled receptor 5(LGR5) Homo sapiens The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015], |
Protein Expression | Placenta, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane,trans-Golgi network membrane, |
Protein Function | function:Orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 17 LRR (leucine-rich) repeats.,tissue specificity:Expressed in skeletal muscle, placenta, spinal cord, and various region of brain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |