ITT0201
ITT0201
- Catalog: ITT0201
- Gene/Protein: IGFALS
- Product Description: Immunotag™ ALS Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | ALS |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352 |
Specificity | ALS Polyclonal Antibody detects endogenous levels of ALS protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | IGFALS |
Accession No. | P35858 P70389 |
Alternate Names | IGFALS; ALS; Insulin-like growth factor-binding protein complex acid labile subunit; ALS |
Description | insulin like growth factor binding protein acid labile subunit(IGFALS) Homo sapiens The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009], |
Protein Expression | Liver,Lung,Plasma,Thymus, |
Subcellular Localization | extracellular region,extracellular space,nucleoplasm,insulin-like growth factor ternary complex,extracellular exosome, |
Protein Function | function:Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.,similarity:Contains 20 LRR (leucine-rich) repeats.,subunit:Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.,tissue specificity:Plasma., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |