ITT0999
ITT0999
- Catalog: ITT0999
- Gene/Protein: CNKSR2
- Product Description: Immunotag™ CNK2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CNK2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from CNK2, at AA range: 610-690 |
| Specificity | CNK2 Polyclonal Antibody detects endogenous levels of CNK2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CNKSR2 |
| Accession No. | Q8WXI2 Q80YA9 Q9Z1T4 |
| Alternate Names | CNKSR2; CNK2; KIAA0902; KSR2; Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; CNK homolog protein 2; CNK2 |
| Description | connector enhancer of kinase suppressor of Ras 2(CNKSR2) Homo sapiens This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009], |
| Protein Expression | Brain,Fetal brain, |
| Subcellular Localization | cytoplasm,Golgi apparatus,plasma membrane,postsynaptic density,membrane,neuron projection,neuronal cell body,postsynaptic membrane,extracellular exosome, |
| Protein Function | function:May function as an adapter protein or regulator of Ras signaling pathways.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CNKSR family.,similarity:Contains 1 CRIC domain.,similarity:Contains 1 DUF1170 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Interacts with RAF1, RAB2L and RAL GTPase proteins., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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