ITT1470
ITT1470
- Catalog: ITT1470
- Gene/Protein: LPAR3
- Product Description: Immunotag™ EDG-7 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | EDG-7 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from EDG-7, at AA range: 80-160 |
Specificity | EDG-7 Polyclonal Antibody detects endogenous levels of EDG-7 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | LPAR3 |
Accession No. | Q9UBY5 Q9EQ31 Q8K5E0 |
Alternate Names | LPAR3; EDG7; LPA3; Lysophosphatidic acid receptor 3; LPA receptor 3; LPA-3; Lysophosphatidic acid receptor Edg-7 |
Description | lysophosphatidic acid receptor 3(LPAR3) Homo sapiens This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Protein Expression | Embryonic kidney,T-cell,Testis, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,axon, |
Protein Function | function:Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |