ITT1887
ITT1887
- Catalog: ITT1887
- Gene/Protein: GUCY1B2
- Product Description: Immunotag™ GCS-β-2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GCS-β-2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from the N-terminal region of human GCS-β-2 |
Specificity | GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | GUCY1B2 |
Accession No. | O75343 P22717 |
Alternate Names | GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2 |
Description | Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation. |
Subcellular Localization | plasma membrane,guanylate cyclase complex, soluble, |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |