ITT2947
ITT2947
- Catalog: ITT2947
- Gene/Protein: MYOM2
- Product Description: Immunotag™ Myomesin-2 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Myomesin-2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Monkey |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human MYOM2. AA range:612-661 |
Specificity | Myomesin-2 Polyclonal Antibody detects endogenous levels of Myomesin-2 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | MYOM2 |
Accession No. | P54296 |
Alternate Names | MYOM2; Myomesin-2; 165 kDa connectin-associated protein; 165 kDa titin-associated protein; M-protein; Myomesin family member 2 |
Description | myomesin 2(MYOM2) Homo sapiens The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008], |
Protein Expression | PNS,Skeletal muscle, |
Subcellular Localization | mitochondrion,M band,myosin filament, |
Protein Function | function:Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.,similarity:Contains 5 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with TTN/titin., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |