ITT4003
ITT4003
- Catalog: ITT4003
- Gene/Protein: RAP2B
- Product Description: Immunotag™ Rap 2B Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Rap 2B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Rap 2B, at AA range: 70-150 |
Specificity | Rap 2B Polyclonal Antibody detects endogenous levels of Rap 2B protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | RAP2B |
Accession No. | P61225 P61226 P61227 |
Alternate Names | RAP2B; Ras-related protein Rap-2b |
Description | RAP2B, member of RAS oncogene family(RAP2B) Homo sapiens This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Placenta,Platelet, |
Subcellular Localization | cytosol,plasma membrane,bicellular tight junction,membrane,cell-cell contact zone,membrane raft,recycling endosome membrane,extracellular exosome, |
Protein Function | domain:The effector domain mediates the interaction with RUNDC3A.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |