ITT4525
ITT4525
- Catalog: ITT4525
- Gene/Protein: TAF1A
- Product Description: Immunotag™ TAF I p48 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TAF I p48 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from TAF I p48, at AA range: 270-350 |
Specificity | TAF I p48 Polyclonal Antibody detects endogenous levels of TAF I p48 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TAF1A |
Accession No. | Q15573 P97357 Q3B7U2 |
Alternate Names | TAF1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; RNA polymerase I-specific TBP-associated factor 48 kDa; TAFI48; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; Transcription factor SL1; |
Description | TATA-box binding protein associated factor, RNA polymerase I subunit A(TAF1A) Homo sapiens This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011], |
Protein Expression | Embryo,Skin, |
Subcellular Localization | RNA polymerase I transcription factor complex,nucleus,nucleoplasm,microtubule cytoskeleton,intracellular membrane-bounded organelle, |
Protein Function | function:Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex).,subunit:Component of the transcription factor SL1/TIFIB complex which is composed of TBP and at least TAF1A, TAF1B and TAF1C. In the complex, interacts directly with TBP, TAF1B and TAF1C. Interaction of the SL1/TIFIB subunits with TBP excludes interaction with the transcription factor IID (TFIID) subunits. This mutually exclusive binding directs the formation of promoter and RNA polymerase-selective TBP-TAF complexes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |