ITT4559
ITT4559
- Catalog: ITT4559
- Gene/Protein: TBC1D3
- Product Description: Immunotag™ TBC1D3A/B/C Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | TBC1D3A/B/C |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human TBC1D3. AA range:481-530 |
Specificity | TBC1D3A/B/C Polyclonal Antibody detects endogenous levels of TBC1D3A/B/C protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TBC1D3 |
Accession No. | Q8IZP1/A6NDS4/Q6IPX1 |
Alternate Names | TBC1D3; PRC17; TBC1D3A; TBC1 domain family member 3; Prostate cancer gene 17 protein; Protein TRE17-alpha; Rab GTPase-activating protein PRC17; TBC1D3B; TBC1D3I; TBC1 domain family member 3B; TBC1D3C; TBC1D3D; TBC1 domain family member 3C |
Description | TBC1 domain family member 3C(TBC1D3C) Homo sapiens This gene represents one of a cluster of related genes found on chromosome 17. The proteins encoded by this gene family contain a TBC (Tre-2, Bub2p, and Cdc16p) domain and may be involved in GTPase signaling and vesicle trafficking. [provided by RefSeq, Apr 2014], |
Protein Expression | Brain,Placenta,Testis, |
Subcellular Localization | intracellular,plasma membrane,endomembrane system, |
Protein Function | disease:May be involved in forms of prostate cancers.,function:Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.,similarity:Contains 1 Rab-GAP TBC domain.,tissue specificity:Expressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers.,tissue specificity:Expressed in pancreas, thymus and testis., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |