ITT5309
ITT5309
- Catalog: ITT5309
- Gene/Protein: MANF
- Product Description: Immunotag™ ARP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ARP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Mesencephalic astrocyte-derived neurotrophic factor at AA range: 1-50 |
| Specificity | ARP Polyclonal Antibody detects endogenous levels of ARP protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | MANF |
| Accession No. | P55145 Q9CXI5 P0C5H9 |
| Alternate Names | MANF; ARMET; ARP; Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET |
| Description | mesencephalic astrocyte derived neurotrophic factor(MANF) Homo sapiens The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014], |
| Protein Expression | Testis, |
| Subcellular Localization | extracellular space,nucleus,endoplasmic reticulum,perinuclear region of cytoplasm, |
| Protein Function | response to unfolded protein, response to organic substance, response to protein stimulus, |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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