ITT5741
ITT5741
- Catalog: ITT5741
- Gene/Protein: CALB2
- Product Description: Immunotag™ Calretinin Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Calretinin |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from calbindin 2 at AA range: 191-240 |
Specificity | Calretinin Polyclonal Antibody detects endogenous levels of calbindin 2 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CALB2 |
Accession No. | P22676 Q08331 P47728 |
Alternate Names | Calretinin (CR) (29 kDa calbindin) |
Description | calbindin 2(CALB2) Homo sapiens This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010], |
Protein Expression | Adipose tissue,Cerebellum,Colon, |
Subcellular Localization | nucleus,cytoplasm,cytosol,gap junction,neuron projection,terminal bouton,synapse, |
Protein Function | function:Calretinin is a calcium-binding protein which is abundant in auditory neurons.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 6 EF-hand domains.,tissue specificity:Brain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |