ITT5799
ITT5799
- Catalog: ITT5799
- Gene/Protein: TIMP4
- Product Description: Immunotag™ TIMP-4 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | TIMP-4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from TIMP-4 at AA range: 174-223 |
Specificity | TIMP-4 Polyclonal Antibody detects endogenous levels of TIMP-4 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | TIMP4 |
Accession No. | Q99727 Q9JHB3 |
Alternate Names | Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4) |
Description | TIMP metallopeptidase inhibitor 4(TIMP4) Homo sapiens This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Heart, |
Subcellular Localization | proteinaceous extracellular matrix,extracellular space,sarcomere, |
Protein Function | function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,tissue specificity:Abundant in heart and present at low levels in many other tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |