This antibody is intended for in vitro diagnostic (IVD) use.
The Cytokeratin 14 (IHC555) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. Use of this antibody is indicated, subsequent to clinical differential diagnoses of diseases, as an aid in the identification of squamous cell carcinomas within the context of antibody panels, the patient’s clinical history and other diagnostic tests evaluated by a qualified pathologist.
Cytokeratin 14 (CK14) is found in squamous epithelial basal cells, myoepithelium, some glandular epithelia, and mesothelial cells. Anti-Cytokeratin 14 is useful for distinguishing squamous cell carcinomas from other epithelial tumors, and for classifying metaplastic breast carcinomas.