ITA0239
ITA0239
- Catalog: ITA0239
- Gene/Protein: TNFRSF10A
- Product Description: Immunotag™ TR10A Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | TR10A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB: 1:500~1:3000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human TR10A |
| Specificity | TR10A antibody detects endogenous levels of total TR10A |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | TNFRSF10A |
| Accession No. | O00220 |
| Alternate Names | Apo2; CD261; Cytotoxic TRAIL receptor; Death receptor 4; DR4; NF related apoptosis-inducing ligand receptor 1; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TR10A_HUMAN; TRAIL receptor 1; TRAIL-R1; TRAILR 1; TRAILR1; Tumor necrosis factor receptor superfamily member 10A; Tumor necrosis factor receptor superfamily member 10a variant 2; Tumor necrosis factor receptor superfamily, member 10a; |
| Description | Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 50kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|