ITA0265
ITA0265
- Catalog: ITA0265
- Gene/Protein: AKAP10
- Product Description: Immunotag™ AKAP10 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | AKAP10 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB: 1:500~1:3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human AKAP10 |
| Specificity | AKAP10 antibody detects endogenous levels of total AKAP10 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | AKAP10 |
| Accession No. | O43572 |
| Alternate Names | 1500031L16Rik; A kinase (PRKA) anchor protein 10; A kinase anchor protein 10; A kinase anchor protein 10 mitochondrial; A-kinase anchor protein 10; AKA10_HUMAN; akap 10; AKAP-10; AKAP10; B130049N18Rik; D AKAP 2; D-AKAP-2; dakap 2; dakap2; Dual specific A kinase anchoring protein 2; Dual specificity A kinase-anchoring protein 2; mgc9410; MGC9414|; Mitochondrial A kinase PPKA anchor protein 10; mitochondrial; prka 10; PRKA10; Protein A kinase anchoring protein 10; Protein A kinase anchoring protein 10 mitochondrial precursor; Protein kinase A anchoring protein 10; Protein kinase A-anchoring protein 10; |
| Description | Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 73kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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