ITA0398
ITA0398
- Catalog: ITA0398
- Gene/Protein: FARP2
- Product Description: Immunotag™ FIR Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | FIR |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500-1:2000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human FIR |
Specificity | FIR Antibody detects endogenous levels of FIR |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | FARP2 |
Accession No. | O94887 |
Alternate Names | FARP2; FARP2_HUMAN; FERM; FERM domain including RhoGEF; FERM, RhoGEF and pleckstrin domain protein 2; FERM, RhoGEF and pleckstrin domain-containing protein 2; FGD1 related Cdc42 GEF; FIR; FRG; KIAA0793; PH domain-containing family C member 3; Pleckstrin homology domain-containing family C member 3; PLEKHC3; RhoGEF and pleckstrin domain protein 2; RhoGEF and pleckstrin domain-containing protein 2; |
Description | Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 119kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |