ITA1096
ITA1096
- Catalog: ITA1096
- Gene/Protein: MAP2K3
- Product Description: Immunotag™ Phospho-MKK3 (Ser189) Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Phospho-MKK3 (Ser189) |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,IF/ICC,ELISA |
Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human MKK3 around the phosphorylation site of Serine 189 |
Specificity | Phospho-MKK3 (Ser189) Antibody detects endogenous levels of MKK3 only when phosphorylated at Serine 189 |
Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | MAP2K3 |
Accession No. | P46734 |
Alternate Names | AW212142; dual specificity mitogen activated protein kinase kinase 3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; map2k3; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3; MEK 3; MEK3; Mitogen activated protein kinase kinase 3; MKK 3; MKK3; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; protein kinase, mitogen-activated, kinase 3; SAPK kinase 2; SAPKK 2; SAPKK2; Stress activated protein kinase kinase 2; |
Description | Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 40kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |