ITA1600
ITA1600
- Catalog: ITA1600
- Gene/Protein: CAV2
- Product Description: Immunotag™ Caveolin 2 (Phospho-Tyr27) Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Caveolin 2 (Phospho-Tyr27) |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-1:2000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human Caveolin 2 (Phospho-Tyr27) |
Specificity | Caveolin 2 (Phospho-Tyr27) Antibody detects endogenous levels of total Caveolin 2 (Phospho-Tyr27) |
Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | CAV2 |
Accession No. | P51636 |
Alternate Names | CAV; CAV2; CAV2_HUMAN; Caveolae protein 20 kD; Caveolin 2; Caveolin 2 isoform a and b; Caveolin-2; MGC12294; OTTHUMP00000025032; OTTHUMP00000195982; |
Description | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 27 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |