ITA1622
ITA1622
- Catalog: ITA1622
- Gene/Protein: MEN1
- Product Description: Immunotag™ SIAH2 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | SIAH2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500-1:2000,IHC 1:50-1:200,IF 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human SIAH2 |
| Specificity | SIAH2 Antibody detects endogenous levels of total SIAH2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | MEN1 |
| Accession No. | O00255 |
| Alternate Names | MEA 1; MEA1; MEN 1; Men1; MEN1_HUMAN; Menin; Multiple Endocrine Adenomatosis 1; Multiple Endocrine Neoplasia 1; SCG 2; SCG2; Suppressor Candidate Gene 2; Wermer syndrome; ZES; Zollinger Ellison Syndrome; |
| Description | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 36 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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