ITA2052
ITA2052
- Catalog: ITA2052
- Gene/Protein: APOBEC3A
- Product Description: Immunotag™ APOBEC3A Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | APOBEC3A |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human APOBEC3A |
Specificity | APOBEC3A Antibody detects endogenous levels of total APOBEC3A |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | APOBEC3A |
Accession No. | P31941 |
Alternate Names | A3A; ABC3A_HUMAN; APOBEC3A; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3A; ARP3; bK150C2.1; Catalytic polypeptide like 3A; Phorbolin 1; Phorbolin-1; PHRBN; Probable DNA dC >dU editing enzyme APOBEC-3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; |
Description | DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 26kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |