ITA2368
ITA2368
- Catalog: ITA2368
- Gene/Protein: VPS54
- Product Description: Immunotag™ VPS54 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | VPS54 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:1000-3000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human VPS54 |
Specificity | VPS54 Antibody detects endogenous levels of total VPS54 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | VPS54 |
Accession No. | Q9P1Q0 |
Alternate Names | HCC8; Hepatocellular carcinoma protein 8; hVps54L; PPP1R164; Protein phosphatase 1 regulatory subunit 164; SLP 8p; Tumor antigen HOM-HCC-8; Tumor antigen SLP 8p; Tumor antigen SLP-8p; Vacuolar protein sorting 54 homolog (S. cerevisiae); Vacuolar protein sorting 54, S. cerevisiae, homolog of; Vacuolar protein sorting associated protein 54; VPS54 GARP complex subunit; VPS54-like; VPS54L; Wobbler, mouse, homolog of; WR; |
Description | Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:18367545). Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling (PubMed:25799061). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 111 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |