ITA2449
ITA2449
- Catalog: ITA2449
- Gene/Protein: COLEC12
- Product Description: Immunotag™ COLEC12 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | COLEC12 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human COLEC12 |
| Specificity | COLEC12 Antibody detects endogenous levels of total COLEC12 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | COLEC12 |
| Accession No. | Q5KU26 |
| Alternate Names | CL P1; CL-P1; CLP1; COL12_HUMAN; COLEC 12; colec12; Collectin placenta 1; Collectin placenta protein 1; Collectin sub family member 12; Collectin-12; hCL P1; hCL-P1; NSR2; Nurse cell scavenger receptor 2; SCARA4; Scavenger receptor class A member 4; Scavenger receptor with C type lectin; Scavenger receptor with C-type lectin; SRCL; |
| Description | Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 82 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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