ITA2960
ITA2960
- Catalog: ITA2960
- Gene/Protein: PRPF8
- Product Description: Immunotag™ PRPF8 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PRPF8 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC |
Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human PRPF8. |
Specificity | PRPF8 antibody detects endogenous levels of PRPF8. |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | PRPF8 |
Accession No. | Q6P2Q9 |
Alternate Names | 220 kDa U5 snRNP specific protein; 220 kDa U5 snRNP-specific protein; Apoptosis regulated protein 1; Apoptosis regulated protein 2; HPRP8; p220; Pre mRNA processing factor 8; Pre mRNA-processing factor 8, S. cerevisiae, homolog of; Pre-mRNA-processing-splicing factor 8; Precursor mRNA processing protein; PRP8; PRP8 homolog; PRP8 pre mRNA processing factor 8 homolog; PRP8_HUMAN; PRPC8; Prpf8; Retinitis pigmentosa 13 (autosomal dominant); RP13; SNRNP220; Splicing factor Prp8; U5 snRNP specific protein; U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p; |
Description | Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 220 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |